Analysis of HPV infection status and influencing factors in patients with uterine lesions

Abstract

Background:
Human papillomavirus (HPV) infection is a key risk factor for the development of cervical and other uterine lesions. Understanding the prevalence and associated factors of HPV infection in patients with uterine lesions can help guide prevention and management strategies.
Objective:
To assess the status of HPV infection and analyze the influencing factors among patients with uterine lesions.
Methods:
A cross-sectional study was conducted on [XXX] patients diagnosed with uterine lesions at [hospital/center] between [start date] and [end date]. Cervical specimens were collected for HPV DNA testing. Patients’ demographic, clinical, and behavioral data were recorded, including age, marital status, parity, smoking, contraceptive use, and history of sexually transmitted infections (STIs). Univariate and multivariate logistic regression analyses were performed to identify factors associated with HPV infection.
Results:
Among [XXX] patients, [XX.X%] tested positive for HPV. High-risk HPV types were detected in [XX.X%], with HPV-16 and HPV-18 being the most common. The prevalence of HPV was significantly higher in women younger than [X] years, those with multiple sexual partners, and those with a history of STIs (p < 0.05). Multivariate analysis showed that younger age (OR = X.X, 95% CI: X.X–X.X), smoking (OR = X.X), and high parity (OR = X.X) were independent risk factors for HPV infection.
Conclusion:
HPV infection is common among patients with uterine lesions, particularly among younger, sexually active women and those with certain behavioral risk factors. Targeted education, vaccination, and regular screening are essential to reduce HPV-related disease burden in this population.
Keywords:
HPV infection, uterine lesions, risk factors, epidemiology, cervical cancer