Detection and analysis of Yersinia pestis antibody in Marmota himalayana serum in Gonghe County of Qinghai Province

Abstract

Background:
Yersinia pestis, the causative agent of plague, persists in natural reservoirs such as Marmota himalayana in Qinghai Province. Monitoring antibody prevalence in these animal hosts is critical for plague surveillance and prevention.
Objective:
To detect and analyze the prevalence of Yersinia pestis antibodies in serum samples of Marmota himalayana collected from Gonghe County, Qinghai Province.
Methods:
Serum samples were collected from [number] Marmota himalayana specimens captured in Gonghe County. Antibody detection was performed using [ELISA, indirect hemagglutination assay, or other specified method]. Positive rates were calculated, and seroprevalence was analyzed by season and geographic location.
Results:
Out of [total number] samples tested, [X%] were positive for Yersinia pestis antibodies. Seroprevalence varied by sampling sites and seasons, with the highest rates observed in [season or location]. These findings indicate ongoing circulation of Y. pestis in local animal reservoirs.
Conclusion:
The detection of Yersinia pestis antibodies in Marmota himalayana highlights the continued risk of plague transmission in Gonghe County. Enhanced surveillance and preventive measures are essential to reduce the risk of human infection.
Keywords:
Yersinia pestis, plague, antibody detection, Marmota himalayana, Gonghe County, Qinghai Province